Creatine is synthesized by arginine, glycine, and methionine in vivo and plays a major role in the energy supply of vertebrate muscles. Because it is 95% present in skeletal muscle and is not detected in Urine, Creatine is used to indirectly measure the amount of Creatine. The Creatine test is performed with other tests to correct the concentration of other substances measured in Urine Almost all creatinine is excreted through the kidneys and is therefore used as an indicator material because it shows stable levels in Urine. The concentration of Urine can change continously throughout the day, so it can be used as a correction factor in random Urine sample measurements. PicoSens™ Creatinine Assay Kit makes it easy and quick to quantify the Creatinine contained in Urine.